<b>CHARACTERISTICS OF NON-ADRENERGIC NON-CHOLINERGIC INHIBITORY POTENTIALS IN </b><b>GUINEA-PIG GASTRIC SMOOTH MUSCLE</b>

THE ROLE OF NON-ADRENERGIC NON-CHOLINERGIC SYSTEM IN THE PERISTALTIC REFLEX OF GUINE A PIG ILEUM

The effect of some endogenous components -endogenous opiates, cholecystokinin (CCK), vasoactive intestinal polypeptide (VIP) and somatostatin-as inhibitory or excitatory transmitters in the local nervous pathways involved in peristaltic responses was examined. The peristaltic reflex was studied using a modification of the Trendelenberg preparation. In each preparation, the luminal distens...

Non-adrenergic, non-cholinergic, non-purinergic contractions of the urothelium/lamina propria of the pig bladder.

Acetylcholine, and to a lesser extent ATP, mediates neurogenic contractions of bladder smooth muscle. Recently, the urothelium and lamina propria have also been shown to have contractile properties, but the neurotransmitters involved in mediating responses to nerve stimulation have not been investigated. Isolated strips of porcine urothelium with lamina propria were electrically field stimulate...

Polar innervation of enteric non-cholinergic and non-adrenergic neurons in the isolated guinea-pig ileum.

To study the polarity of the efferent pathway of the myenteric plexus, recordings were made of the mechanical activity of the longitudinal muscle of isolated guinea-pig ileal segments upon stimulation with an electrical field around the myenteric plexus contained within strips of longitudinal muscle (LM-MP) continuous with each end of ileal segment. The amplitude of the contractile response to ...

Inhaled ammonium persulphate inhibits non-adrenergic, non-cholinergic relaxations in the guinea pig isolated trachea.

BACKGROUND Persulphates can act both as irritants and sensitizers in inducing occupational asthma. A dysfunction of nervous control regulating the airway tone has been hypothesized as a mechanism underlying bronchoconstriction in asthma. OBJECTIVES It was the aim of this study to investigate whether inhaled ammonium persulphate affects the non-adrenergic, non-cholinergic (NANC) inhibitory inn...

Glucose Does Not Activate Non-Adrenergic, Non-Cholinergic (NANC) Inhibitory Neurons in the Rat Stomach